Across TCGA cell cohorts, KDM4D RNA expression is significantly associated with the go_rna of many other GO terms, with 4,339 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KDM4D-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase II promoter, DNA-templated transcription initiation, and Protein-DNA complex organization. Each is linked with KDM4D in more than 13 cancer types. Because this analysis shows association rather than direction, both KDM4D-to-partner and partner-to-KDM4D results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM4D→partner) and Y-score (partner→KDM4D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Transcription initiation at RNA polymerase II promoter →	+0.070	+0.576	<.001	<.001	3	14
STOMACH	DNA-templated transcription initiation →	+0.065	+0.599	<.001	<.001	3	14
LARGE_INTESTINE	Protein-DNA complex organization →	+0.063	+0.385	<.001	<.001	3	14
SOFT_TISSUE	Regulation of cell cycle checkpoint →	+0.092	+0.495	<.001	<.001	3	14
LARGE_INTESTINE	Protein-DNA complex assembly →	+0.060	+0.350	<.001	<.001	3	13
PANCREAS	Negative regulation of cell cycle phase transition →	+0.064	+0.429	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,339 associations by consensus.

Exploration

KDM4D survival (RNA) · tumor vs normal (RNA) · all KDM4D data types