KDM4C

Across TCGA patient cohorts, KDM4C RNA expression is significantly associated with the protein abundance of many other proteins, with 7,480 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KDM4C-associated proteins across cancer lineages are PSIP1, CDC37L1, and DENND4C. Each is linked with KDM4C in more than 5 cancer types. Because this analysis shows association rather than direction, both KDM4C-to-partner and partner-to-KDM4C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM4C versus PSIP1 in GBM, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM4C→partner) and Y-score (partner→KDM4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PSIP1 →	+0.410	+0.348	.003	.001	3	6
HNSC	CDC37L1 →	+0.338	+0.501	<.001	<.001	2	6
LSCC	DENND4C →	+0.213	+0.420	.003	<.001	3	5
GBM	MTAP →	+0.667	+0.487	<.001	<.001	3	5
HNSC	UHRF2 →	+0.427	+0.860	<.001	<.001	3	5
GBM	PLAA →	+0.263	+0.357	.009	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,480 associations by consensus.

KDM4C vs PSIP1 — GBM

Explore this scatter interactively →