KDM4C

Across TCGA patient cohorts, KDM4C protein abundance is significantly associated with the RNA expression of many other genes, with 4,626 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KDM4C-associated genes across cancer lineages are CA9, PNN, and KDM3A. Each is linked with KDM4C in more than 3 cancer types. Because this analysis shows association rather than direction, both KDM4C-to-partner and partner-to-KDM4C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM4C versus CA9 in GBM, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM4C→partner) and Y-score (partner→KDM4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CA9 →	+2.124	+0.800	<.001	<.001	3	4
HNSC	PNN →	+0.659	+0.698	.008	.009	3	3
HNSC	KDM3A →	+0.797	+0.930	.007	.001	3	3
CCRCC	GARNL3 →	+0.426	+0.585	.007	.004	3	2
HNSC	B3GNT6 →	+1.395	+0.846	<.001	<.001	3	2
GBM	AURKAP2 →	-0.291	-0.594	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,626 associations by consensus.

KDM4C vs CA9 — GBM

Explore this scatter interactively →