KDM3B

Across TCGA patient cohorts, KDM3B protein abundance is significantly associated with the RNA expression of many other genes, with 21,146 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KDM3B-associated genes across cancer lineages are LARS1, CDKN2AIPNL, and MRPL22. Each is linked with KDM3B in more than 7 cancer types. Because this analysis shows association rather than direction, both KDM3B-to-partner and partner-to-KDM3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM3B versus LARS1 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM3B→partner) and Y-score (partner→KDM3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LARS1 →	+0.659	+0.304	<.001	.001	3	8
HNSC	CDKN2AIPNL →	+0.911	+0.284	<.001	<.001	3	8
HNSC	MRPL22 →	+0.621	+0.279	<.001	<.001	3	8
BRCA	EARS2 →	+0.622	+0.193	<.001	.001	3	7
HNSC	PAIP2 →	+0.730	+0.212	.002	.005	3	7
LSCC	TMEM177 →	+0.613	+0.263	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,146 associations by consensus.

KDM3B vs LARS1 — OV

Explore this scatter interactively →