KDM3B

Across TCGA cell cohorts, KDM3B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,862 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KDM3B-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Epigenetic regulation of gene expression, and Nucleic acid transport. Each is linked with KDM3B in more than 15 cancer types. Because this analysis shows association rather than direction, both KDM3B-to-partner and partner-to-KDM3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by KDM3B-low versus KDM3B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM3B→partner) and Y-score (partner→KDM3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.078	+0.931	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.076	+1.096	<.001	<.001	3	16
CNS	Nucleic acid transport →	+0.093	+0.519	<.001	<.001	3	16
CNS	RNA transport →	+0.093	+0.519	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	RNA export from nucleus →	+0.109	+0.824	<.001	<.001	3	16
KIDNEY	Positive regulation of gene expression, epigenetic →	+0.072	+0.691	<.001	.006	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,862 associations by consensus.

Positive regulation of organelle assembly by KDM3B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →