KDM2B-DT

Across TCGA pan-cancer cohorts, KDM2B-DT RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated KDM2B-DT data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher KDM2B-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated KDM2B-DT expression acts as an unfavorable survival marker, although some lineages such as BRCA and HNSC show a favorable association.

BRCA, KIRC, and HNSC are the cancer types where KDM2B-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.979	0.945	<.001	123	view →
KIRC	OS	Median	All	0.538	0.699	<.001	87	view →
HNSC	OS	Quartile	IV	0.604	0.362	.003	77	view →
PAAD	OS	Median	All	0.533	0.261	<.001	60	view →
LIHC	OS	Tertile	All	0.623	0.851	<.001	47	view →
LUSC	DFS	Tertile	III,IV	0.411	1.000	.006	41	view →
ACC	DFS	Tertile	All	0.515	0.779	.003	26	view →
LGG	OS	Median	All	0.944	0.832	<.001	22	view →
LUAD	OS	Median	All	0.433	0.299	.001	17	view →
PRAD	DFS	Median	All	0.844	0.923	.005	12	view →
ESCA	DFS	Tertile	All	1.000	0.453	.014	9	view →
KIRP	DFS	Quartile	All	0.511	0.782	.009	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

KDM2B-DT–BRCA (OS)

Open the BRCA breakdown →