KDM1B

Across TCGA patient cohorts, KDM1B protein abundance is significantly associated with the RNA expression of many other genes, with 14,750 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KDM1B-associated genes across cancer lineages are NUP153, ASH2L, and NSD3. Each is linked with KDM1B in more than 5 cancer types. Because this analysis shows association rather than direction, both KDM1B-to-partner and partner-to-KDM1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KDM1B versus NUP153 in LSCC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM1B→partner) and Y-score (partner→KDM1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NUP153 →	+0.659	+0.362	<.001	<.001	3	6
LSCC	ASH2L →	+0.852	+0.392	<.001	<.001	3	6
LSCC	NSD3 →	+1.248	+0.461	<.001	<.001	3	6
LSCC	POMK →	+0.793	+0.284	<.001	<.001	3	6
LSCC	KLHL23 →	+0.882	+0.281	<.001	<.001	3	6
BRCA	CTSO →	-0.810	-0.432	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,750 associations by consensus.

KDM1B vs NUP153 — LSCC

Explore this scatter interactively →