KDM1B

Across TCGA cell cohorts, KDM1B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,987 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KDM1B-associated GO terms across cancer lineages are Genomic imprinting, Negative regulation of RNA export from nucleus, and Epigenetic programming of gene expression. Each is linked with KDM1B in more than 17 cancer types. Because this analysis shows association rather than direction, both KDM1B-to-partner and partner-to-KDM1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Genomic imprinting grouped by KDM1B-low versus KDM1B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDM1B→partner) and Y-score (partner→KDM1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Genomic imprinting →	+0.253	+1.420	<.001	<.001	3	18
LIVER	Negative regulation of RNA export from nucleus →	+0.146	+1.158	.002	.003	3	14
LIVER	Epigenetic programming of gene expression →	+0.112	+0.986	.001	.007	2	12
LUNG_NSCLC_LUAD	Regulation of RNA export from nucleus →	+0.112	+0.939	<.001	<.001	3	11
SKIN	Maintenance of presynaptic active zone structure →	+0.700	+0.735	.005	.001	3	9
SKIN	Transcription initiation-coupled chromatin remodeling →	+0.062	+0.884	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,987 associations by consensus.

Genomic imprinting by KDM1B expression — STOMACH

Explore this box plot interactively →