KDELR3

Across TCGA cell cohorts, KDELR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,390 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KDELR3-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, Carbohydrate derivative catabolic process, and COPII-coated vesicle cargo loading. Each is linked with KDELR3 in more than 16 cancer types. Because this analysis shows association rather than direction, both KDELR3-to-partner and partner-to-KDELR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by KDELR3-low versus KDELR3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDELR3→partner) and Y-score (partner→KDELR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of protein exit from endoplasmic reticulum →	+0.135	+2.600	<.001	<.001	3	17
LUNG_SCLC	Carbohydrate derivative catabolic process →	+0.084	+2.453	<.001	<.001	3	15
BONE	COPII-coated vesicle cargo loading →	+0.179	+3.356	<.001	<.001	3	14
SOFT_TISSUE	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.068	+2.009	<.001	.001	3	13
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.163	+3.209	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Maintenance of protein location in cell →	+0.171	+2.937	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,390 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by KDELR3 expression — SOFT_TISSUE

Explore this box plot interactively →