KDELR3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KDELR3 protein abundance is significantly associated with the go_rna of many other GO terms, with 580 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible KDELR3-associated GO terms across cancer lineages are Negative regulation of cytoskeleton organization, Head morphogenesis, and Protein sulfation. Each is linked with KDELR3 in more than 2 cancer types. Because this analysis shows association rather than direction, both KDELR3-to-partner and partner-to-KDELR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cytoskeleton organization grouped by KDELR3-low versus KDELR3-high in OVARY.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KDELR3→partner) and Y-score (partner→KDELR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYNegative regulation of cytoskeleton organization →+0.062+2.047.006.00333
OVARYHead morphogenesis →+0.123+1.975.008.00533
BREASTProtein sulfation →-1.826-2.910<.001.00832
BREASTNegative regulation of inclusion body assembly →+0.221+1.898.006.00723
OVARYEpithelial cell fate commitment →-0.229-2.464<.001.00123
OVARYSynaptic vesicle priming →-0.131-2.164<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 580 associations by consensus.

Negative regulation of cytoskeleton organization by KDELR3 expression — OVARY

Box plot of Negative regulation of cytoskeleton organization in KDELR3-low vs KDELR3-high samples in OVARY.

Explore this box plot interactively →

Exploration