KCTD9

Across TCGA pan-cancer cohorts, KCTD9 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KCTD9 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher KCTD9 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KCTD9 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, PDAC, and CCRCC are the cancer types where KCTD9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	1.000	0.826	.011	22	view →
PDAC	OS	Tertile	III,IV	0.586	0.235	.007	17	view →
CCRCC	DFS	Tertile	III,IV	1.000	0.694	.006	13	view →
LUAD	OS	Tertile	II,III,IV	0.464	1.000	.022	3	view →
HNSC	DFS	Quartile	All	0.751	0.909	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KCTD9–UCEC (DFS)

Open the UCEC breakdown →