KCTD9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCTD9 mutation is significantly associated with the RNA expression of many other genes, with 3,179 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD9-associated genes across cancer lineages are SNORD114-5, RNA5SP146, and GRPEL2P2. Each is linked with KCTD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD9-to-partner and partner-to-KCTD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD114-5 grouped by KCTD9-low versus KCTD9-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD9→partner) and Y-score (partner→KCTD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCASNORD114-5 →+0.336+7.640<.001.00932
UCECRNA5SP146 →+0.245+1.940<.001.00832
UCECGRPEL2P2 →+0.080+1.796<.001.00832
UCECLINC02038 →+0.407+3.678.005.00132
UCECTCP11X3P →+0.209+1.654<.001.00732
UCECRNA5SP419 →+0.582+2.077<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,179 associations by consensus.

SNORD114-5 by KCTD9 expression — BLCA

Box plot of SNORD114-5 in KCTD9-low vs KCTD9-high samples in BLCA.

Explore this box plot interactively →

Exploration