Across TCGA cell cohorts, KCTD8 RNA expression is significantly associated with the go_rna of many other GO terms, with 540 significant associations in total. CNS shows the largest number of these associations.

The most reproducible KCTD8-associated GO terms across cancer lineages are rRNA modification, Positive regulation of type B pancreatic cell apoptotic process, and Potassium ion transport. Each is linked with KCTD8 in more than 5 cancer types. Because this analysis shows association rather than direction, both KCTD8-to-partner and partner-to-KCTD8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD8→partner) and Y-score (partner→KCTD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	rRNA modification →	+0.046	+0.327	.001	.003	2	6
OVARY	Positive regulation of type B pancreatic cell apoptotic process →	-0.161	-0.183	.001	.002	3	5
OVARY	Potassium ion transport →	-0.052	-0.158	.001	.008	3	4
OVARY	Mitochondrion organization →	+0.044	+0.168	<.001	.004	3	4
LUNG_SCLC	Nucleobase transport →	+0.113	+0.725	.001	.004	3	4
BLOOD_Leukemia	Ribosomal small subunit biogenesis →	+0.051	+0.179	.002	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 540 associations by consensus.

Exploration

KCTD8 survival (RNA) · tumor vs normal (RNA) · all KCTD8 data types