KCTD7

Across TCGA cell cohorts, KCTD7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,045 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KCTD7-associated GO terms across cancer lineages are Membrane hyperpolarization, Cell division, and Regulation of smoothened signaling pathway. Each is linked with KCTD7 in more than 17 cancer types. Because this analysis shows association rather than direction, both KCTD7-to-partner and partner-to-KCTD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane hyperpolarization grouped by KCTD7-low versus KCTD7-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD7→partner) and Y-score (partner→KCTD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Membrane hyperpolarization →	+1.604	+1.283	<.001	<.001	3	18
BREAST	Cell division →	+0.120	+0.928	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Regulation of smoothened signaling pathway →	+0.055	+0.858	<.001	.003	3	13
LUNG_NSCLC_LUSC	Golgi to plasma membrane protein transport →	+0.165	+1.211	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome, telomeric region →	+0.120	+0.887	<.001	.001	3	11
STOMACH	Regulation of clathrin-dependent endocytosis →	+0.068	+0.847	.003	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,045 associations by consensus.

Membrane hyperpolarization by KCTD7 expression — OESOPHAGUS

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