KCTD7

Across TCGA cell cohorts, KCTD7 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCTD7-associated genes across cancer lineages are CCDC182, OR2D3, and ETDC. Each is linked with KCTD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD7-to-partner and partner-to-KCTD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC182 grouped by KCTD7-low versus KCTD7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD7→partner) and Y-score (partner→KCTD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC182 →	+0.073	+5.217	<.001	<.001	3	1
LARGE_INTESTINE	OR2D3 →	+0.024	+4.095	.003	.009	3	1
LARGE_INTESTINE	ETDC →	+0.595	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CCDC182 by KCTD7 expression — LARGE_INTESTINE

Explore this box plot interactively →