KCTD6

Across TCGA patient cohorts, KCTD6 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,108 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KCTD6-associated proteins across cancer lineages are PPP4R2, QRICH1, and SH3BGRL3. Each is linked with KCTD6 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCTD6-to-partner and partner-to-KCTD6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD6 versus PPP4R2 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD6→partner) and Y-score (partner→KCTD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPP4R2 →	+0.280	+0.424	<.001	<.001	3	5
OV	QRICH1 →	+0.297	+0.585	<.001	<.001	3	5
OV	SH3BGRL3 →	-0.317	-0.464	.003	.005	3	5
GBM	CSTA →	-1.051	-0.553	<.001	<.001	3	5
BRCA	KIAA1143 →	+0.326	+0.779	<.001	<.001	3	5
BRCA	APPL1 →	+0.276	+0.904	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,108 associations by consensus.

KCTD6 vs PPP4R2 — LSCC

Explore this scatter interactively →