KCTD6

Across TCGA patient cohorts, KCTD6 protein abundance is significantly associated with the RNA expression of many other genes, with 7,055 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KCTD6-associated genes across cancer lineages are TTLL9, TRMO, and RASA4B. Each is linked with KCTD6 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCTD6-to-partner and partner-to-KCTD6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD6 versus TTLL9 in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD6→partner) and Y-score (partner→KCTD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TTLL9 →	+0.694	+0.611	<.001	<.001	3	3
PDAC	TRMO →	+0.466	+0.574	.009	<.001	3	3
GBM	RASA4B →	+0.625	+0.414	<.001	<.001	3	3
PDAC	RPS7 →	-0.358	-0.577	.004	.008	3	3
BRCA	SLC26A11 →	+0.599	+0.517	<.001	<.001	3	3
BRCA	GSTM2 →	+0.992	+0.539	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,055 associations by consensus.

KCTD6 vs TTLL9 — BRCA

Explore this scatter interactively →