KCTD6

Across TCGA patient cohorts, KCTD6 mutation is significantly associated with the RNA expression of many other genes, with 1,315 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD6-associated genes across cancer lineages are MIR7852, RNA5SP489, and RNU6-178P. Each is linked with KCTD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD6-to-partner and partner-to-KCTD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7852 grouped by KCTD6-low versus KCTD6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD6→partner) and Y-score (partner→KCTD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7852 →	+0.089	+3.668	.007	.009	3	2
BRCA	RNA5SP489 →	+0.388	+8.471	<.001	.005	3	2
UCEC	RNU6-178P →	+0.661	+2.250	<.001	<.001	3	2
UCEC	MTATP6P21 →	+0.297	+2.060	<.001	.002	3	2
UCEC	RNU6-718P →	+0.110	+3.140	.003	.004	3	2
BRCA	RN7SL539P →	+0.169	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,315 associations by consensus.

MIR7852 by KCTD6 expression — UCEC

Explore this box plot interactively →