KCTD6

Across TCGA cell cohorts, KCTD6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,868 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCTD6-associated GO terms across cancer lineages are Cellular response to lipopolysaccharide, Regulation of mRNA export from nucleus, and Regulation of ribonucleoprotein complex localization. Each is linked with KCTD6 in more than 10 cancer types. Because this analysis shows association rather than direction, both KCTD6-to-partner and partner-to-KCTD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to lipopolysaccharide grouped by KCTD6-low versus KCTD6-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD6→partner) and Y-score (partner→KCTD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cellular response to lipopolysaccharide →	-0.056	-1.013	<.001	.001	3	11
PANCREAS	Regulation of mRNA export from nucleus →	+0.120	+1.126	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of ribonucleoprotein complex localization →	+0.102	+0.704	.002	.008	2	11
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair →	+0.087	+1.195	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Cellular response to molecule of bacterial origin →	-0.089	-0.718	<.001	.007	3	10
BLOOD_Leukemia	Negative regulation of synaptic transmission, cholinergic →	-0.765	-0.433	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,868 associations by consensus.

Cellular response to lipopolysaccharide by KCTD6 expression — BREAST

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