KCTD5

Across TCGA patient cohorts, KCTD5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,100 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KCTD5-associated genes across cancer lineages are HLF, CEP68, and CAVIN2. Each is linked with KCTD5 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCTD5-to-partner and partner-to-KCTD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD5 versus HLF in CCRCC, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD5→partner) and Y-score (partner→KCTD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HLF →	-1.261	-0.525	<.001	<.001	3	5
HNSC	CEP68 →	-0.556	-0.244	<.001	<.001	3	5
CCRCC	CAVIN2 →	-1.022	-0.291	.001	.009	3	5
BRCA	RALGAPA1 →	-0.789	-0.323	<.001	<.001	3	5
OV	PLK4 →	+0.618	+0.296	.006	.006	3	4
OV	CDCA5 →	+0.873	+0.345	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,100 associations by consensus.

KCTD5 vs HLF — CCRCC

Explore this scatter interactively →