KCTD3

Across TCGA patient cohorts, KCTD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,469 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCTD3-associated proteins across cancer lineages are KCTD3_S664, KCTD3_S711, and IPO9. Each is linked with KCTD3 in more than 8 cancer types. Because this analysis shows association rather than direction, both KCTD3-to-partner and partner-to-KCTD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD3 versus KCTD3_S664 in CCRCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD3→partner) and Y-score (partner→KCTD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KCTD3_S664 →	+0.914	+0.820	<.001	<.001	3	9
LUAD	KCTD3_S711 →	+0.729	+0.742	<.001	<.001	3	9
LSCC	IPO9 →	+0.300	+0.642	<.001	<.001	3	6
GBM	MYO1G →	-0.570	-0.298	<.001	<.001	3	6
LSCC	CDC73 →	+0.381	+0.867	<.001	<.001	3	6
LSCC	GATAD2B →	+0.378	+0.773	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,469 associations by consensus.

KCTD3 vs KCTD3_S664 — CCRCC

Explore this scatter interactively →