KCTD3

Across TCGA patient cohorts, KCTD3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,450 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCTD3-associated genes across cancer lineages are COL4A3, COL4A4, and MTR. Each is linked with KCTD3 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCTD3-to-partner and partner-to-KCTD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD3 versus COL4A3 in LUAD, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD3→partner) and Y-score (partner→KCTD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	COL4A3 →	-1.555	-0.442	<.001	<.001	3	5
LUAD	COL4A4 →	-1.362	-0.462	<.001	<.001	3	5
UCEC	MTR →	+0.495	+0.233	<.001	.001	3	5
COAD	BTF3 →	+0.521	+0.518	.001	.006	3	4
BRCA	LINC00092 →	-0.197	-0.294	.001	<.001	3	4
BRCA	ATP8B1 →	+1.054	+0.367	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,450 associations by consensus.

KCTD3 vs COL4A3 — LUAD

Explore this scatter interactively →