KCTD3

Across TCGA cell cohorts, KCTD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,419 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KCTD3-associated GO terms across cancer lineages are Establishment of protein localization to endoplasmic reticulum membrane, Nuclear pore organization, and Regulation of endoplasmic reticulum tubular network organization. Each is linked with KCTD3 in more than 12 cancer types. Because this analysis shows association rather than direction, both KCTD3-to-partner and partner-to-KCTD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to endoplasmic reticulum membrane grouped by KCTD3-low versus KCTD3-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD3→partner) and Y-score (partner→KCTD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Establishment of protein localization to endoplasmic reticulum membrane →	+0.115	+0.758	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Nuclear pore organization →	+0.136	+0.932	<.001	<.001	3	11
KIDNEY	Regulation of endoplasmic reticulum tubular network organization →	+0.131	+0.856	.002	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA damage checkpoint →	+0.097	+0.949	<.001	.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of endoplasmic reticulum tubular network organization →	+0.190	+1.119	.001	.006	3	9
SOFT_TISSUE	mRNA 3'-end processing →	+0.076	+0.610	.002	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,419 associations by consensus.

Establishment of protein localization to endoplasmic reticulum membrane by KCTD3 expression — KIDNEY

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