Across TCGA patient cohorts, KCTD21 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,871 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KCTD21-associated proteins across cancer lineages are PLAT, SSH3_S37, and DNMT1_S714. Each is linked with KCTD21 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCTD21-to-partner and partner-to-KCTD21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD21→partner) and Y-score (partner→KCTD21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PLAT →	+0.724	+0.288	<.001	<.001	3	5
PDAC	SSH3_S37 →	+1.391	+0.428	<.001	<.001	3	4
BRCA	DNMT1_S714 →	-0.666	-0.642	<.001	<.001	3	4
PDAC	EXOC3 →	+0.178	+0.285	.001	<.001	3	4
GBM	EXOSC2 →	-0.280	-0.338	<.001	<.001	3	4
PDAC	RPL12 →	-0.179	-0.317	.009	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,871 associations by consensus.

Exploration

KCTD21 survival (RNA) · tumor vs normal (RNA) · all KCTD21 data types