Across TCGA patient cohorts, KCTD21 protein abundance is significantly associated with the RNA expression of many other genes, with 8,616 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KCTD21-associated genes across cancer lineages are MGP, CTSK, and NEMP1. Each is linked with KCTD21 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCTD21-to-partner and partner-to-KCTD21 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD21→partner) and Y-score (partner→KCTD21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MGP →	+1.857	+0.375	<.001	.001	3	5
COAD	CTSK →	+0.783	+0.307	.002	.007	3	5
UCEC	NEMP1 →	-0.525	-0.250	<.001	.001	3	5
OV	CSDC2 →	+0.860	+0.350	.001	.001	3	5
GBM	HELLS →	-0.885	-0.285	<.001	<.001	3	5
CCRCC	CCDC80 →	+1.520	+0.221	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,616 associations by consensus.

Exploration

KCTD21 survival (RNA) · tumor vs normal (RNA) · all KCTD21 data types