KCTD21

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCTD21 mutation is significantly associated with the RNA expression of many other genes, with 1,453 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD21-associated genes across cancer lineages are RNA5SP478, RNU6-492P, and RNA5SP113. Each is linked with KCTD21 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD21-to-partner and partner-to-KCTD21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD21→partner) and Y-score (partner→KCTD21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNA5SP478 →+0.473+6.008<.001.00232
LUSCRNU6-492P →+0.209+5.906<.001.00132
UCECRNA5SP113 →+0.523+3.226<.001.00132
UCECPLSCR5-AS1 →+0.060+3.219.002.00432
SKCMRNA5SP68 →+0.227+4.867<.001.00532
UCECBTBD10 →+0.523+2.238.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,453 associations by consensus.

Exploration