Across TCGA cell cohorts, KCTD21 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,151 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KCTD21-associated GO terms across cancer lineages are Endosomal transport, Macroautophagy, and Cytosolic transport. Each is linked with KCTD21 in more than 15 cancer types. Because this analysis shows association rather than direction, both KCTD21-to-partner and partner-to-KCTD21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD21→partner) and Y-score (partner→KCTD21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Endosomal transport →	+0.061	+0.806	<.001	<.001	3	16
STOMACH	Macroautophagy →	+0.082	+1.110	<.001	<.001	3	16
BONE	Cytosolic transport →	+0.064	+0.767	.002	.005	3	15
BONE	Vesicle-mediated transport to the plasma membrane →	+0.101	+1.392	<.001	<.001	3	15
STOMACH	Positive regulation of autophagy →	+0.054	+0.931	.006	.004	3	14
OESOPHAGUS	Positive regulation of macroautophagy →	+0.072	+0.948	.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,151 associations by consensus.

Exploration

KCTD21 survival (RNA) · tumor vs normal (RNA) · all KCTD21 data types