KCTD20

Across TCGA pan-cancer cohorts, KCTD20 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KCTD20 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher KCTD20 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KCTD20 expression acts as an unfavorable survival marker, although some lineages such as HNSC and GBM show a favorable association.

HNSC, GBM, and LUAD are the cancer types where KCTD20 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	II,III,IV	0.890	0.351	.031	4	view →
GBM	DFS	Quartile	All	0.435	0.226	.041	2	view →
LUAD	OS	Quartile	All	1.000	0.796	.026	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KCTD20–HNSC (DFS)

Open the HNSC breakdown →