KCTD20

Across TCGA patient cohorts, KCTD20 mutation is significantly associated with the RNA expression of many other genes, with 1,657 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD20-associated genes across cancer lineages are PDE7B, OR51A7, and RNU6-132P. Each is linked with KCTD20 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD20-to-partner and partner-to-KCTD20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDE7B grouped by KCTD20-low versus KCTD20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD20→partner) and Y-score (partner→KCTD20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDE7B →	-0.435	-2.226	.007	.002	3	2
UCEC	OR51A7 →	+0.077	+2.114	.002	.001	3	2
LIHC	RNU6-132P →	+0.361	+5.355	<.001	.005	3	2
UCEC	RN7SL191P →	+0.138	+2.579	<.001	<.001	3	2
UCEC	RNA5SP413 →	+0.965	+1.639	<.001	.008	3	2
UCEC	RNA5SP422 →	+0.654	+1.764	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,657 associations by consensus.

PDE7B by KCTD20 expression — UCEC

Explore this box plot interactively →