KCTD20

Across TCGA cell cohorts, KCTD20 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,868 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCTD20-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, Protein peptidyl-prolyl isomerization, and DNA damage tolerance. Each is linked with KCTD20 in more than 14 cancer types. Because this analysis shows association rather than direction, both KCTD20-to-partner and partner-to-KCTD20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA export from nucleus grouped by KCTD20-low versus KCTD20-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD20→partner) and Y-score (partner→KCTD20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of RNA export from nucleus →	+0.174	+1.114	<.001	<.001	3	15
BLOOD_Myeloma	Protein peptidyl-prolyl isomerization →	+0.126	+0.764	<.001	<.001	3	13
BLOOD_Lymphoma	DNA damage tolerance →	+0.058	+0.931	.002	.001	3	12
BLOOD_Lymphoma	Mitotic nuclear division →	+0.082	+1.074	<.001	<.001	3	12
OVARY	Peptidyl-proline modification →	+0.126	+0.868	<.001	.001	3	11
CNS	Mitotic G2/M transition checkpoint →	+0.057	+0.651	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,868 associations by consensus.

Negative regulation of RNA export from nucleus by KCTD20 expression — PANCREAS

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