KCTD2

Across TCGA patient cohorts, KCTD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,701 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCTD2-associated proteins across cancer lineages are SEC24A, RRBP1, and SPCS3. Each is linked with KCTD2 in more than 5 cancer types. Because this analysis shows association rather than direction, both KCTD2-to-partner and partner-to-KCTD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD2 versus SEC24A in CCRCC, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD2→partner) and Y-score (partner→KCTD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SEC24A →	-0.391	-0.398	<.001	<.001	3	6
CCRCC	RRBP1 →	-0.374	-0.285	.001	.003	2	6
LUAD	SPCS3 →	-0.564	-0.416	<.001	<.001	3	5
GBM	BIN2_S444 →	-0.762	-0.432	<.001	<.001	3	5
GBM	CRELD2 →	-0.552	-0.396	<.001	<.001	3	5
LUAD	FKBP11 →	-0.549	-0.341	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,701 associations by consensus.

KCTD2 vs SEC24A — CCRCC

Explore this scatter interactively →