KCTD19

Across TCGA cell cohorts, KCTD19 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,720 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCTD19-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Regulation of G1/S transition of mitotic cell cycle, and Establishment of protein localization to organelle. Each is linked with KCTD19 in more than 10 cancer types. Because this analysis shows association rather than direction, both KCTD19-to-partner and partner-to-KCTD19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by KCTD19-low versus KCTD19-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD19→partner) and Y-score (partner→KCTD19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.108	+1.308	<.001	<.001	3	11
BREAST	Regulation of G1/S transition of mitotic cell cycle →	+0.055	+0.440	<.001	.003	3	10
BLOOD_Leukemia	Establishment of protein localization to organelle →	+0.039	+0.842	<.001	.001	3	10
KIDNEY	Negative regulation of myoblast fusion →	+0.109	+1.308	<.001	<.001	3	9
BLOOD_Lymphoma	Cytoplasmic translation →	+0.069	+0.581	<.001	<.001	3	9
STOMACH	Positive regulation of DNA metabolic process →	+0.042	+0.412	.001	.009	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,720 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by KCTD19 expression — KIDNEY

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