KCTD19

Across TCGA cell cohorts, KCTD19 mutation is significantly associated with the RNA expression of many other genes, with 345 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCTD19-associated genes across cancer lineages are MAGEB4, GNPNAT1, and ZNF391. Each is linked with KCTD19 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCTD19-to-partner and partner-to-KCTD19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by KCTD19-low versus KCTD19-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD19→partner) and Y-score (partner→KCTD19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MAGEB4 →	+0.046	+4.705	<.001	.003	3	3
LARGE_INTESTINE	GNPNAT1 →	+0.468	+2.244	.006	.003	3	2
LARGE_INTESTINE	ZNF391 →	+0.648	+2.158	.006	.004	3	2
LARGE_INTESTINE	LARP1B →	+0.692	+3.459	<.001	.001	3	2
LARGE_INTESTINE	ACSM6 →	+0.013	+2.362	.001	.001	3	2
LARGE_INTESTINE	C2orf69 →	+0.439	+3.584	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 345 associations by consensus.

MAGEB4 by KCTD19 expression — BLOOD_Leukemia

Explore this box plot interactively →