KCTD15

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCTD15 protein abundance is significantly associated with the RNA expression of many other genes, with 15,457 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCTD15-associated genes across cancer lineages are SDSL, GAN, and BMP7. Each is linked with KCTD15 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCTD15-to-partner and partner-to-KCTD15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCTD15 versus SDSL in GBM, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD15→partner) and Y-score (partner→KCTD15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSDSL →-0.605-0.601<.001<.00135
LSCCGAN →+0.720+0.529<.001<.00135
HNSCBMP7 →+1.310+0.401.005.00934
LSCCDENND3 →-0.600-0.644<.001<.00134
LSCCCSF3R →-1.004-0.524<.001<.00134
HNSCCCRL2 →-0.924-0.650<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,457 associations by consensus.

KCTD15 vs SDSL — GBM

Per-sample scatter of KCTD15 vs SDSL in GBM (Pearson r = -0.45).

Explore this scatter interactively →

Exploration