KCTD15

Across TCGA cell cohorts, KCTD15 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCTD15-associated genes across cancer lineages are GJD2, FAM205A, and GSG1L2. Each is linked with KCTD15 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD15-to-partner and partner-to-KCTD15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GJD2 grouped by KCTD15-low versus KCTD15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD15→partner) and Y-score (partner→KCTD15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GJD2 →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	FAM205A →	+0.019	+3.766	.001	.004	3	1
LARGE_INTESTINE	GSG1L2 →	+0.013	+4.022	<.001	.006	3	1
BLOOD_Leukemia	CCKAR →	+0.043	+4.409	<.001	.005	3	1
BLOOD_Leukemia	BPIFB6 →	+0.047	+4.969	<.001	.003	3	1
BLOOD_Leukemia	CCT8L2 →	+0.014	+4.874	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

GJD2 by KCTD15 expression — LARGE_INTESTINE

Explore this box plot interactively →