KCTD13

Across TCGA patient cohorts, KCTD13 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD13-associated genes across cancer lineages are PRAS40_pT246, STAT5a, and Tuberin_pT1462. Each is linked with KCTD13 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD13-to-partner and partner-to-KCTD13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAS40_pT246 grouped by KCTD13-low versus KCTD13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD13→partner) and Y-score (partner→KCTD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRAS40_pT246 →	+0.174	+2.335	.044	.020	3	1
UCEC	STAT5a →	+0.527	+3.459	.008	.005	3	1
UCEC	Tuberin_pT1462 →	+0.289	+2.321	.012	.035	3	1
UCEC	CD49b →	-0.333	-2.980	.019	.036	3	1
UCEC	p27_pT198 →	+0.109	+2.321	.042	.035	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PRAS40_pT246 by KCTD13 expression — UCEC

Explore this box plot interactively →