KCTD13

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KCTD13 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCTD13-associated genes across cancer lineages are OR10A5, ELSPBP1, and OR10AG1. Each is linked with KCTD13 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD13-to-partner and partner-to-KCTD13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10A5 grouped by KCTD13-low versus KCTD13-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD13→partner) and Y-score (partner→KCTD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYOR10A5 →+0.028+4.029<.001.00931
OVARYELSPBP1 →+0.140+4.029.005.00931
LUNG_NSCLC_LUADOR10AG1 →+0.032+4.662<.001.00531
LARGE_INTESTINECPLX4 →+0.038+3.766<.001.00431
LARGE_INTESTINEACSM6 →+0.027+4.584<.001<.00131
LARGE_INTESTINECFHR2 →+0.038+4.022<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OR10A5 by KCTD13 expression — OVARY

Box plot of OR10A5 in KCTD13-low vs KCTD13-high samples in OVARY.

Explore this box plot interactively →

Exploration