KCTD12

Across TCGA patient cohorts, KCTD12 mutation is significantly associated with the RNA expression of many other genes, with 911 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD12-associated genes across cancer lineages are RNU6-210P, RN7SKP295, and YTHDF3-AS1. Each is linked with KCTD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD12-to-partner and partner-to-KCTD12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-210P grouped by KCTD12-low versus KCTD12-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD12→partner) and Y-score (partner→KCTD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-210P →	+0.392	+5.978	<.001	.002	3	2
UCEC	RN7SKP295 →	+0.305	+3.242	<.001	<.001	3	2
UCEC	YTHDF3-AS1 →	+0.852	+3.491	<.001	.002	3	1
UCEC	RNU6-94P →	+0.865	+3.671	<.001	.001	3	1
UCEC	MIR98 →	+0.377	+2.801	<.001	.001	3	1
UCEC	H4C12 →	+0.569	+3.248	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 911 associations by consensus.

RNU6-210P by KCTD12 expression — LUSC

Explore this box plot interactively →