KCTD12

Across TCGA cell cohorts, KCTD12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,080 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible KCTD12-associated GO terms across cancer lineages are Translational elongation, Negative regulation of type I interferon-mediated signaling pathway, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with KCTD12 in more than 6 cancer types. Because this analysis shows association rather than direction, both KCTD12-to-partner and partner-to-KCTD12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Translational elongation grouped by KCTD12-low versus KCTD12-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD12→partner) and Y-score (partner→KCTD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Translational elongation →	+0.052	+1.525	<.001	.001	3	7
LUNG_NSCLC_LUAD	Negative regulation of type I interferon-mediated signaling pathway →	+0.076	+1.182	<.001	<.001	3	7
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.098	+1.304	<.001	.001	3	7
LIVER	Response to heat →	+0.069	+1.446	.001	<.001	3	6
BREAST	Maintenance of location in cell →	+0.080	+1.700	<.001	<.001	3	6
SOFT_TISSUE	Neurotransmitter secretion →	-0.058	-1.474	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,080 associations by consensus.

Translational elongation by KCTD12 expression — STOMACH

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