Across TCGA patient cohorts, KCTD11 protein abundance is significantly associated with the RNA expression of many other genes, with 221 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KCTD11-associated genes across cancer lineages are DNAJC5, ESRP2, and TULP2. Each is linked with KCTD11 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD11-to-partner and partner-to-KCTD11 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD11→partner) and Y-score (partner→KCTD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DNAJC5 →	+0.864	+1.138	<.001	<.001	3	1
HNSC	ESRP2 →	+0.812	+1.312	.006	.002	3	1
HNSC	TULP2 →	-0.416	-1.353	<.001	.003	3	1
HNSC	TFPI2 →	-2.140	-1.174	.002	.001	3	1
HNSC	CHORDC1 →	-1.983	-1.610	.007	.001	3	1
HNSC	CCN6 →	-2.929	-1.237	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 221 associations by consensus.

Exploration

KCTD11 survival (RNA) · tumor vs normal (RNA) · all KCTD11 data types