Across TCGA patient cohorts, KCTD11 mutation is significantly associated with the RNA expression of many other genes, with 1,529 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD11-associated genes across cancer lineages are RNU6-99P, SRCIN1, and TRAV14DV4. Each is linked with KCTD11 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCTD11-to-partner and partner-to-KCTD11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD11→partner) and Y-score (partner→KCTD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-99P →	+0.089	+3.812	<.001	.008	3	3
UCEC	SRCIN1 →	-0.724	-2.087	<.001	.006	3	2
COAD	TRAV14DV4 →	+0.870	+3.223	<.001	.009	3	2
COAD	MIR6798 →	+0.246	+3.917	<.001	.009	3	2
COAD	TXNL1 →	+0.505	+3.223	.003	.009	3	2
COAD	HAUS1 →	+0.607	+3.223	.006	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,529 associations by consensus.

Exploration

KCTD11 survival (RNA) · tumor vs normal (RNA) · all KCTD11 data types