KCTD1

Across TCGA patient cohorts, KCTD1 mutation is significantly associated with the RNA expression of many other genes, with 3,794 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCTD1-associated genes across cancer lineages are RNU6-982P, MRGPRX1, and RNA5SP198. Each is linked with KCTD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCTD1-to-partner and partner-to-KCTD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-982P grouped by KCTD1-low versus KCTD1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD1→partner) and Y-score (partner→KCTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-982P →	+1.021	+7.930	<.001	.008	3	2
CESC	MRGPRX1 →	+0.225	+3.816	<.001	.007	3	2
CESC	RNA5SP198 →	+0.241	+4.559	<.001	.006	3	2
COAD	APOBEC3H →	+0.590	+3.459	.001	.005	3	2
UCEC	PHF5A →	+0.535	+4.087	<.001	<.001	3	2
COAD	GSKIP →	+0.972	+3.321	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,794 associations by consensus.

RNU6-982P by KCTD1 expression — LUAD

Explore this box plot interactively →