KCTD1

Across TCGA cell cohorts, KCTD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,232 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCTD1-associated GO terms across cancer lineages are Gliogenesis, ATP synthesis coupled electron transport, and Mitochondrial ATP synthesis coupled electron transport. Each is linked with KCTD1 in more than 8 cancer types. Because this analysis shows association rather than direction, both KCTD1-to-partner and partner-to-KCTD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gliogenesis grouped by KCTD1-low versus KCTD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCTD1→partner) and Y-score (partner→KCTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Gliogenesis →	+0.075	+0.995	.003	.004	2	9
BLOOD_Lymphoma	ATP synthesis coupled electron transport →	+0.069	+0.654	<.001	<.001	3	8
BLOOD_Lymphoma	Mitochondrial ATP synthesis coupled electron transport →	+0.069	+0.654	<.001	<.001	3	8
LARGE_INTESTINE	Negative regulation of smoothened signaling pathway →	+0.044	+1.309	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Cellular response to jasmonic acid stimulus →	+1.180	+1.292	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Response to jasmonic acid →	+1.180	+1.292	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,232 associations by consensus.

Gliogenesis by KCTD1 expression — BONE

Explore this box plot interactively →