KCP

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KCP mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KCP data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher KCP mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated KCP expression acts as an unfavorable survival marker.

CCRCC, PDAC, and UCEC are the cancer types where KCP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianIII,IV0.2020.985.00719view →
PDACDFSQuartileII,III,IV0.2830.727.00718view →
UCECOSQuartileAll0.8361.000.0302view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KCP–CCRCC (OS)

Kaplan–Meier survival curve for KCP mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration