KCP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCP protein abundance is significantly associated with the RNA expression of many other genes, with 5,430 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KCP-associated genes across cancer lineages are PIP5K1B, PECR, and DPY19L2. Each is linked with KCP in more than 1 cancer types. Because this analysis shows association rather than direction, both KCP-to-partner and partner-to-KCP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCP versus PIP5K1B in PDAC, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCP→partner) and Y-score (partner→KCP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACPIP5K1B →-1.598-0.836.002.00132
UCECPECR →+0.803+0.750.001.00532
UCECDPY19L2 →+0.928+0.528.004.00332
UCECHOGA1 →+0.929+0.797.001.00232
UCECATP6V1FNB →+0.796+0.908<.001<.00132
PDACPWWP3B →+1.109+0.830.008.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,430 associations by consensus.

KCP vs PIP5K1B — PDAC

Per-sample scatter of KCP vs PIP5K1B in PDAC (Pearson r = -0.58).

Explore this scatter interactively →

Exploration