KCNV2

Across TCGA cell cohorts, KCNV2 mutation is significantly associated with the RNA expression of many other genes, with 388 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNV2-associated genes across cancer lineages are OR10K2, OR10T2, and SPINK9. Each is linked with KCNV2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNV2-to-partner and partner-to-KCNV2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10K2 grouped by KCNV2-low versus KCNV2-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNV2→partner) and Y-score (partner→KCNV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR10K2 →	+0.031	+3.781	<.001	.009	3	2
BREAST	OR10T2 →	+0.091	+3.781	<.001	.009	3	2
SKIN	SPINK9 →	+0.058	+5.415	<.001	.004	3	2
STOMACH	C16orf92 →	+0.186	+4.129	<.001	.007	3	2
LARGE_INTESTINE	FBXW10 →	+0.149	+2.800	.008	.001	3	2
SOFT_TISSUE	OR10Q1 →	+0.167	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 388 associations by consensus.

OR10K2 by KCNV2 expression — BREAST

Explore this box plot interactively →