KCNT2

Across TCGA cell cohorts, KCNT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,454 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible KCNT2-associated GO terms across cancer lineages are Protein localization to nucleus, Cytoplasmic translation, and Regulation of DNA-templated transcription initiation. Each is linked with KCNT2 in more than 8 cancer types. Because this analysis shows association rather than direction, both KCNT2-to-partner and partner-to-KCNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nucleus grouped by KCNT2-low versus KCNT2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNT2→partner) and Y-score (partner→KCNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Protein localization to nucleus →	+0.044	+0.546	.004	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.086	+0.210	<.001	.001	3	9
OVARY	Regulation of DNA-templated transcription initiation →	+0.057	+0.563	<.001	.006	3	8
OVARY	Negative regulation of gene expression, epigenetic →	+0.068	+0.799	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of protein localization to Cajal body →	+0.064	+0.207	<.001	.005	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein localization to Cajal body →	+0.064	+0.207	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,454 associations by consensus.

Protein localization to nucleus by KCNT2 expression — OVARY

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