KCNS3

Across TCGA patient cohorts, KCNS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,044 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCNS3-associated proteins across cancer lineages are PFN1, SCFD1, and VCAN_S1351. Each is linked with KCNS3 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNS3-to-partner and partner-to-KCNS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNS3 versus PFN1 in LSCC, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNS3→partner) and Y-score (partner→KCNS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PFN1 →	-0.206	-0.710	<.001	.001	3	4
LSCC	SCFD1 →	-0.183	-0.592	<.001	<.001	3	4
BRCA	VCAN_S1351 →	+1.201	+0.783	<.001	.002	3	4
HNSC	SRM →	-0.296	-1.249	<.001	<.001	3	3
BRCA	BIN2_S273 →	-0.607	-1.032	<.001	<.001	3	3
LSCC	MAP2 →	+0.957	+0.894	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,044 associations by consensus.

KCNS3 vs PFN1 — LSCC

Explore this scatter interactively →