KCNS3

Across TCGA cell cohorts, KCNS3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,132 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNS3-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Cytoplasmic translation, and Regulation of myoblast fusion. Each is linked with KCNS3 in more than 9 cancer types. Because this analysis shows association rather than direction, both KCNS3-to-partner and partner-to-KCNS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by KCNS3-low versus KCNS3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNS3→partner) and Y-score (partner→KCNS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.090	+1.669	<.001	.001	3	10
BLOOD_Lymphoma	Cytoplasmic translation →	+0.071	+0.569	<.001	.001	3	9
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.093	+0.584	<.001	.001	3	8
BREAST	Endosomal transport →	+0.042	+1.382	.001	.006	3	8
URINARY_TRACT	Protein stabilization →	+0.053	+2.358	.001	.001	3	8
OVARY	CD8-positive, alpha-beta T cell differentiation →	+0.103	+1.881	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,132 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by KCNS3 expression — OVARY

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