KCNS2

Across TCGA cell cohorts, KCNS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,093 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNS2-associated GO terms across cancer lineages are Endosomal transport, Microtubule polymerization, and Double-strand break repair. Each is linked with KCNS2 in more than 10 cancer types. Because this analysis shows association rather than direction, both KCNS2-to-partner and partner-to-KCNS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by KCNS2-low versus KCNS2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNS2→partner) and Y-score (partner→KCNS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Endosomal transport →	+0.062	+0.093	<.001	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Microtubule polymerization →	+0.078	+0.076	.003	.009	3	11
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.060	+0.076	.003	.006	3	10
UPPER_AERODIGESTIVE_TRACT	DNA damage checkpoint signaling →	+0.087	+0.060	<.001	.009	3	10
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via homologous recombination →	+0.069	+0.077	.002	.006	3	10
LUNG_NSCLC_LUAD	Recombinational repair →	+0.057	+0.075	<.001	.004	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,093 associations by consensus.

Endosomal transport by KCNS2 expression — URINARY_TRACT

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